Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604501 | 1.00 | DPP4 (0.49) | DPP4JAK3HPGDPOLBMEN1 | |
| SCHEMBL11860116 | 1.00 | DPP4 (0.49) | DPP4JAK3HPGDPOLBMEN1 | |
| SCHEMBL7072829 | 0.83 | HPGD (0.56) | DPP4JAK3HPGDPOLBMEN1 | |
| SCHEMBL7072835 | 0.83 | HPGD (0.56) | DPP4JAK3HPGDPOLBMEN1 | |
| SCHEMBL259126 | 0.83 | NPSR1 (0.55) | POLBMEN1KMT2ATP53L3MBTL1 | |
| SCHEMBL14826655 | 0.79 | POLB (0.46) | HPGDPOLBMEN1KMT2AGAA | |
| SCHEMBL7069093 | 0.79 | HPGD (0.51) | DPP4HPGDPOLBMEN1KMT2A | |
| SCHEMBL9352214 | 0.79 | HPGD (0.56) | DPP4HPGDPOLBMEN1KMT2A | |
| SCHEMBL2392383 | 0.79 | HPGD (0.56) | DPP4HPGDPOLBMEN1KMT2A | |
| SCHEMBL7069083 | 0.79 | HPGD (0.51) | DPP4HPGDPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103204867-A | chiral alpha-amino boric acid esters, a preparation method and an application in the synthesis of bortezomib thereof | CHENGDU AIQUN TECHNOLOGY CO LTD | 2013-07-17 | — | — | CN | disclosed |