SCHEMBL7072829

SCHEMBL7072829

O=C(Nc1ccccc1)[C@@H]1CCN1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.56
MAPT P10636 4/20 0.54
GAA P10253 3/20 0.54
POLB P06746 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
GFER P55789 1/20 0.54
DPP4 P27487 1/20 0.50
DDB1 Q16531 1/20 0.50
CRBN Q96SW2 1/20 0.50
GLA P06280 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47
EPHX1 P07099 1/20 0.47
TSHR P16473 1/20 0.47
EPHX2 P34913 1/20 0.47
CDK9 P50750 1/20 0.47
CLK4 Q9HAZ1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7072835 1.00 HPGD (0.56) HPGDMAPTGAAPOLBMEN1
SCHEMBL7069083 0.95 HPGD (0.51) HPGDMAPTGAAPOLBMEN1
SCHEMBL7069093 0.95 HPGD (0.51) HPGDMAPTGAAPOLBMEN1
SCHEMBL2392383 0.91 HPGD (0.56) HPGDMAPTGAAPOLBMEN1
SCHEMBL9352214 0.91 HPGD (0.56) HPGDMAPTGAAPOLBMEN1
SCHEMBL2172641 0.91 HPGD (0.56) HPGDMAPTGAAPOLBMEN1
SCHEMBL516052 0.90 HPGD (0.58) HPGDMAPTGAAPOLBMEN1
SCHEMBL13708499 0.90 HPGD (0.58) HPGDMAPTGAAPOLBMEN1
Hydrochloric Acid SCHEMBL4306381 0.90 SCN3A (0.56) HPGDMAPTGAAPOLBMEN1
Hydrochloric Acid SCHEMBL3266984 0.89 HPGD (0.57) HPGDMAPTGAAPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030120088-A1 Optically active azetidincarboxamide-coordinated transition metal complexes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-06-26 US disclosed
EP-1319660-A1 Optically active azetidincarboxamide-coordinated transition metal complexes as catalysts in asymmetric reduction SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120088-A1 Optically active azetidincarboxamide-coordinated transition metal complexes AAAS, AP1M1, AP2A1 HPGD 4448/4885MAPT 4413/4885GAA 2464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.