Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | GUCY1A1 | Q02108 | 7/20 | 0.54 |
| ▸ | GUCY1B1 | Q02153 | 7/20 | 0.54 |
| ▸ | PDE5A | O76074 | 11/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907472 | 0.86 | PDE5A (0.57) | PDE5A | |
| SCHEMBL27907475 | 0.83 | PDE5A (0.60) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL327098 | 0.82 | PDE5A (0.62) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL174664 | 0.80 | GUCY1A1 (0.59) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL174847 | 0.80 | ADORA3 (0.67) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL9913975 | 0.79 | PDE5A (0.57) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| Hydrochloric Acid SCHEMBL15732830 | 0.79 | GUCY1A1 (0.58) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| Hydrochloric Acid SCHEMBL18496411 | 0.79 | ADORA3 (0.66) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| Hydrochloric Acid SCHEMBL1930775 | 0.79 | ADORA3 (0.66) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL325995 | 0.79 | PDE5A (0.59) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103180327-A | Fused-ring 4-aminopyrimidines and their use as stimulators of soluble guanylate cyclase | Bayer Pharma AG | 2013-06-26 | — | — | CN | disclosed |