Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MLYCD | O95822 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 6/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864576 | 0.82 | KMT2A (0.66) | HPGDLMNAMLYCDMEN1KMT2A | |
| SCHEMBL923670 | 0.81 | LMNA (0.58) | HPGDLMNAMLYCDMEN1KMT2A | |
| SCHEMBL24713109 | 0.80 | MLYCD (0.67) | HPGDLMNAMLYCDMEN1KMT2A | |
| SCHEMBL3853133 | 0.80 | CCR1 (0.62) | HPGDLMNAMLYCDMEN1KMT2A | |
| SCHEMBL5227678 | 0.78 | MLYCD (0.86) | HPGDLMNAMLYCDMEN1KMT2A | |
| SCHEMBL23447721 | 0.78 | MLYCD (0.77) | HPGDLMNAMLYCDMEN1KMT2A | |
| SCHEMBL1052230 | 0.78 | MLYCD (0.63) | HPGDLMNAMLYCDMEN1KMT2A | |
| SCHEMBL31173731 | 0.78 | MLYCD (0.63) | HPGDLMNAMLYCDMEN1KMT2A | |
| SCHEMBL26625392 | 0.78 | LMNA (0.69) | HPGDLMNAMLYCDMEN1KMT2A | |
| SCHEMBL10491484 | 0.78 | KMT2A (0.67) | HPGDLMNAMLYCDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103435562-B | 6-replaces Benzodiazepine-2,4-cyclohexadione compounds and uses thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-02-24 | — | — | CN | disclosed |
| CN-103435562-A | 6-substituted benzodiazepine-2,4-diketone compound and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2013-12-11 | — | — | CN | disclosed |