Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929424 | 0.82 | PIM1 (0.47) | PIM1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL29918465 | 0.80 | MAOB (0.55) | KMT2ARAB9AL3MBTL1MAOBNPC1 | |
| SCHEMBL24170723 | 0.80 | MAOB (0.55) | KMT2ARAB9AL3MBTL1MAOBNPC1 | |
| SCHEMBL13545135 | 0.76 | HSP90AB1 (0.53) | PIM1KMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL11629513 | 0.73 | ALDH1A1 (0.61) | KMT2ARAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13545143 | 0.73 | MAOB (0.67) | MAOB | |
| SCHEMBL29215273 | 0.72 | ALDH1A1 (0.59) | KMT2ARAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL23643781 | 0.70 | POLB (0.53) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL29254632 | 0.69 | SMN1; SMN2 (0.47) | KMT2ARAB9ASMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL11263612 | 0.69 | IDO1 (0.53) | RAB9ASMN1; SMN2L3MBTL1MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214506-A | Benzofuran or naphthofuran derivative and preparation method thereof | UNIV SHANGHAI | 2013-07-24 | — | — | CN | disclosed |