Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929427 | 0.82 | PIM1 (0.43) | PIM1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL11732295 | 0.81 | MAOB (0.54) | IDO1KMT2ALMNAMEN1RAB9A | |
| SCHEMBL29170941 | 0.75 | KDM4E (0.57) | IDO1KMT2ALMNAMEN1PLAU | |
| SCHEMBL3282190 | 0.69 | PTPN1 (0.62) | KMT2ALMNAMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7129795 | 0.69 | MEN1 (0.62) | KMT2ALMNAMEN1L3MBTL1USP2 | |
| SCHEMBL12781520 | 0.68 | IDO1 (0.45) | IDO1KMT2ALMNAMEN1PLAU | |
| SCHEMBL1515809 | 0.66 | PLAU (0.73) | KMT2ALMNAPLAUSMN1; SMN2RAB9A | |
| SCHEMBL1887681 | 0.66 | SRD5A2 (0.44) | CSNK2A2CSNK2BCSNK2A1CSNK2A3IDO1 | |
| SCHEMBL23643781 | 0.65 | POLB (0.53) | KMT2AMEN1SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL24471022 | 0.65 | MAOB (0.66) | KMT2AMEN1SMN1; SMN2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214506-A | Benzofuran or naphthofuran derivative and preparation method thereof | UNIV SHANGHAI | 2013-07-24 | — | — | CN | disclosed |