Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951450 | 0.84 | — | — | |
| SCHEMBL29741974 | 0.84 | — | — | |
| SCHEMBL17143638 | 0.83 | RXRA (0.31) | — | |
| SCHEMBL30701761 | 0.83 | RXRA (0.31) | — | |
| SCHEMBL23749845 | 0.82 | GABRA1 (0.39) | GABRA1GABRB1P2RX3P2RX2 | |
| SCHEMBL27946831 | 0.80 | — | — | |
| SCHEMBL20001452 | 0.78 | RPS6KA3 (0.35) | GABRA1RPS6KA3P2RX3P2RX2ALOX5AP | |
| SCHEMBL25613928 | 0.78 | GABRA1 (0.37) | GABRA1GABRB1P2RX3P2RX2 | |
| SCHEMBL18101355 | 0.77 | TLR8 (0.36) | RPS6KA3P2RX3P2RX2ALOX5APFEN1 | |
| SCHEMBL25927987 | 0.77 | GABRA1 (0.35) | GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103403001-A | Novel heterocyclic derivatives and their use in the treatment of neurological disorders | NOVARTIS AG | 2013-11-20 | — | — | CN | disclosed |