Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946950 | 0.83 | CHEK1 (0.44) | KDM4EHTTALDH1A1GAAHPGD | |
| SCHEMBL1701337 | 0.76 | KDR (0.50) | KDRHTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL1701303 | 0.74 | GLS (0.48) | KDRSMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL28777342 | 0.71 | POLB (0.47) | KDM4EHTTMAPTNPC1RAB9A | |
| SCHEMBL14514301 | 0.70 | CHEK1 (0.61) | KDM4EHTTSMN1; SMN2MAPTKMT2A | |
| 4-Nitrophenyl Acetate SCHEMBL74985 | 0.69 | GAA (0.66) | SMN1; SMN2MAPTKMT2AALDH1A1GAA | |
| SCHEMBL27888023 | 0.68 | GAA (0.54) | SMN1; SMN2MAPTKMT2ANPC1RAB9A | |
| SCHEMBL6211088 | 0.68 | HSPB1 (0.55) | HTTSMN1; SMN2MAPTKMT2ARAB9A | |
| SCHEMBL6208447 | 0.67 | HSPB1 (0.65) | HTTSMN1; SMN2MAPTKMT2AALDH1A1 | |
| 4-Nitrophenyl Acetate SCHEMBL11309107 | 0.67 | GAA (0.64) | SMN1; SMN2MAPTKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450152-A | Anti-tumor medicine in double-aryl urea structure based on indazole, indole, azaindazole or azaindole | JINAN HAILE MEDICAL TECHNOLOGY DEV CO LTD | 2013-12-18 | — | — | CN | disclosed |