Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28858613 | 0.91 | CA2 (0.48) | CA2MEN1ALDH1A1TSHRKMT2A | |
| Hydrogen Peroxide SCHEMBL28071225 | 0.90 | CA2 (0.59) | CA2MEN1ALDH1A1TSHRKMT2A | |
| Potassium Ion SCHEMBL28242937 | 0.90 | CA2 (0.59) | CA2MEN1ALDH1A1TSHRKMT2A | |
| Potassium Ion SCHEMBL27408688 | 0.90 | CA2 (0.59) | CA2MEN1ALDH1A1TSHRKMT2A | |
| Bicarbonate SCHEMBL8405677 | 0.90 | CA4 (0.39) | MEN1ALDH1A1TSHRKMT2ACA4 | |
| Acetic Acid SCHEMBL27895513 | 0.88 | CA2 (0.46) | CA2MEN1ALDH1A1TSHRKMT2A | |
| Bicarbonate SCHEMBL25247505 | 0.88 | CA2 (0.50) | CA2MEN1ALDH1A1TSHRKMT2A | |
| Bicarbonate SCHEMBL28163394 | 0.88 | CA2 (0.50) | CA2MEN1ALDH1A1TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL28723276 | 0.87 | CA2 (0.56) | CA2MEN1ALDH1A1TSHRKMT2A | |
| Potassium Ion SCHEMBL29047790 | 0.87 | CA2 (0.56) | CA2MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112094471-B | Composite test material for testing whether cable is water-entering or not and preparation method and application thereof | 中电保力（北京）科技有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-111944477-B | Heat-conducting type bi-component pouring sealant and preparation method thereof | 中电保力（北京）科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112094471-A | Composite test material for testing whether cable is water-entering or not and preparation method and application thereof | 中电保力（北京）科技有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-111944477-A | Heat-conducting type bi-component pouring sealant and preparation method thereof | 中电保力（北京）科技有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-106517217-B | A kind of preparation method of hud typed silica solution | 嘉兴昊特新材料科技有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-106517217-A | Preparation method of core-shell type silica sol | 嘉兴昊特新材料科技有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-103159995-B | Application of polymer particle with chlorine on the surface as thermal reversible reactive filler and composition of polymer particle with chlorine on the surface | UNIV BEIJING CHEMICAL | 2014-11-12 | — | — | CN | disclosed |
| CN-103159995-A | Application of polymer particle with chlorine on the surface as thermal reversible reactive filler and composition of polymer particle with chlorine on the surface | UNIV BEIJING CHEMICAL | 2013-06-19 | — | — | CN | disclosed |