Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477242 | 0.85 | KMT2A (0.70) | KMT2AGAASMN1; SMN2ALDH1A1NHERF1 | |
| SCHEMBL28360388 | 0.80 | LMNA (0.54) | KMT2AGAASMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL3044325 | 0.74 | CYP1A2 (0.66) | KMT2AALDH1A1CA1CA2CA9 | |
| SCHEMBL1706125 | 0.73 | SMN1; SMN2 (0.59) | KMT2AGAASMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL419933 | 0.73 | CA12 (0.59) | KMT2ASMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL22995612 | 0.71 | HPGD (0.56) | KMT2ASMN1; SMN2ALDH1A1NHERF1MEN1 | |
| SCHEMBL27350238 | 0.71 | LMNA (0.50) | KMT2AGAAALDH1A1CA1CA2 | |
| SCHEMBL942572 | 0.70 | PLK1 (0.56) | GAASMN1; SMN2CA2LMNAMAPT | |
| SCHEMBL1449858 | 0.70 | TDP1 (0.63) | KMT2AGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9844671 | 0.70 | LOXL2 (0.54) | KMT2AGAASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679242-B | Ethylidene hydrazine carboxamide derivatives, preparation process and pharmaceutical use thereof | SHANGHAI HENGRUI PHARM CO LTD | 2013-07-10 | — | — | CN | disclosed |