Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675782 | 0.77 | ESR1 (0.63) | RAB9AMAPTKDM4ELMNAESR1 | |
| SCHEMBL14529039 | 0.77 | BACE1 (0.52) | MAPTESR1 | |
| SCHEMBL13675658 | 0.76 | ESR1 (0.67) | MAPTMEN1KMT2ALMNAESR1 | |
| SCHEMBL20353541 | 0.76 | RAB9A (0.67) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL18985299 | 0.76 | RAB9A (0.74) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL18985301 | 0.76 | RAB9A (0.74) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL27752045 | 0.75 | RAB9A (0.67) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL3040770 | 0.75 | RAB9A (0.69) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL27752021 | 0.75 | RAB9A (0.67) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL3040771 | 0.75 | RAB9A (0.69) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214472-A | Preparation of two novel non-ATP (Adenosine Triphosphate) competitive FGFR1 (Fibroblast Growth Factor Receptor1) inhibitors and anti-tumor activity of two novel non-ATP competitive FGFR1 inhibitors | WENZHOU MEDICAL COLLEGE | 2013-07-24 | — | — | CN | disclosed |