Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395127 | 0.92 | HTT (0.53) | HTTMAPK1CA12CA1CA2 | |
| SCHEMBL143861 | 0.92 | HTT (0.53) | HTTMAPK1CA12CA1CA2 | |
| SCHEMBL1457340 | 0.92 | CTNNB1 (0.50) | HTTMAPK1KDM4EHPGDHSD17B10 | |
| Water SCHEMBL7618236 | 0.90 | HTT (0.52) | HTTMAPK1CA12CA1CA2 | |
| SCHEMBL6003587 | 0.89 | HTT (0.59) | HTTMAPK1CA12CA1CA2 | |
| SCHEMBL28260571 | 0.87 | HTT (0.62) | HTTMAPK1CA12CA1CA2 | |
| SCHEMBL30815836 | 0.86 | AKR1C3 (0.54) | HTTMAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL4649585 | 0.86 | AKR1C3 (0.54) | HTTMAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL10699812 | 0.86 | HNF4A (0.49) | HTTMAPK1CA12CA1CA2 | |
| SCHEMBL3826756 | 0.85 | HTT (0.65) | HTTMAPK1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103694702-A | Polyimide solvent cast films having a low coefficient of thermal expansion and method of manufacture thereof | SABIC INNOVATIVE PLASTICS IP | 2014-04-02 | — | — | CN | claimed |
| CN-101627074-B | Articles comprising polyimide solvent cast film having low coefficient of thermal expansion and method of manufacture thereof | SABIC INNOVATIVE PLASTICS IP | 2014-02-12 | — | — | CN | claimed |
| CN-102947389-B | Transparent polyimide-polyester compositions, methods of making, and articles | SABIC INNOVATIVE PLASTICS IP | 2014-11-05 | — | — | CN | disclosed |
| CN-103890063-A | Polyetherimide/ poly(biphenyl ether sulfone) foam materials | SOLVAY SPECIALTY POLYMERS USA | 2014-06-25 | — | — | CN | disclosed |
| CN-103694702-A | Polyimide solvent cast films having a low coefficient of thermal expansion and method of manufacture thereof | SABIC INNOVATIVE PLASTICS IP | 2014-04-02 | — | — | CN | disclosed |
| CN-101627074-B | Articles comprising polyimide solvent cast film having low coefficient of thermal expansion and method of manufacture thereof | SABIC INNOVATIVE PLASTICS IP | 2014-02-12 | — | — | CN | disclosed |
| CN-102516600-B | Compositions and methods for polymer composites | SABIC INNOVATIVE PLASTICS IP | 2013-12-25 | — | — | CN | disclosed |
| CN-103476871-A | Flame retardant poly (siloxane) copolymer compositions, methods of manufacture, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP | 2013-12-25 | — | — | CN | disclosed |