SCHEMBL4649585

SCHEMBL4649585

O=C(c1ccccc1)c1cccc(Oc2cccc(C(=O)O)c2C(=O)O)c1Oc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.54
MYC P01106 1/20 0.46
ELANE P08246 1/20 0.46
CDC25B P30305 2/20 0.45
ATM Q13315 1/20 0.45
POLB P06746 2/20 0.44
NR4A1 P22736 1/20 0.44
HTT P42858 1/20 0.43
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 3/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
CDC25A P30304 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ESR1 P03372 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
HMGB1 P09429 1/20 0.41
TSHR P16473 1/20 0.41
GGT1 P19440 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30815836 1.00 AKR1C3 (0.54) AKR1C3MYCELANECDC25BATM
SCHEMBL3694635 0.89 AKR1C3 (0.59) AKR1C3MYCELANECDC25BATM
SCHEMBL27929972 0.86 HTT (0.47) AKR1C3HTTMAPK1HSD17B10KDM4E
SCHEMBL6003587 0.82 HTT (0.59) AKR1C3NR4A1HTTMAPK1HSD17B10
SCHEMBL29395127 0.82 HTT (0.53) AKR1C3NR4A1HTTMAPK1HSD17B10
SCHEMBL143861 0.82 HTT (0.53) AKR1C3NR4A1HTTMAPK1HSD17B10
SCHEMBL1457340 0.82 CTNNB1 (0.50) AKR1C3POLBHTTMAPK1HSD17B10
SCHEMBL10659207 0.82 LIG1 (0.45) AKR1C3ELANEPOLBHTTMAPK1
SCHEMBL9646984 0.82 CTNNB1 (0.50) AKR1C3ELANEPOLBHTTGAA
SCHEMBL4649583 0.81 HTT (0.54) AKR1C3ELANECDC25BHTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103694702-A Polyimide solvent cast films having a low coefficient of thermal expansion and method of manufacture thereof SABIC INNOVATIVE PLASTICS IP 2014-04-02 CN claimed
CN-101627074-B Articles comprising polyimide solvent cast film having low coefficient of thermal expansion and method of manufacture thereof SABIC INNOVATIVE PLASTICS IP 2014-02-12 CN claimed
CN-110511565-A The composition of enhancing SOLVAY SPECIALTY POLYMERS USA 2019-11-29 CN disclosed
CN-110483993-A Adhesive-bonded fabric and related compound material and manufacturing method SABIC GLOBAL TECHNOLOGIES BV 2019-11-22 CN disclosed
CN-110461906-A The blend of aromatic polymer and the adduct obtained by it SOLVAY SPECIALTY POLYMERS USA 2019-11-15 CN disclosed
CN-110387039-A The control of polycondensation stoichiometry 沙特基础工业全球技术有限公司 2019-10-29 CN disclosed
CN-103443484-B For the polymeric bearing article used in hyperpressure and speed environment 索尔维特殊聚合物美国有限责任公司 2017-07-18 CN disclosed
CN-104470990-B Flame retardant compositions and goods 沙特基础全球技术有限公司 2016-10-19 CN disclosed
CN-106033182-A Tubular member, tubular member unit, intermediate transfer member, and image forming apparatus 富士施乐株式会社 2016-10-19 CN disclosed
CN-105555535-A Fiber-reinforced polyaryletherketone resin composition SABIC GLOBAL TECHNOLOGIES BV 2016-05-04 CN disclosed
CN-105431576-A High temperature melt integrity battery separators via spinning SABIC INNOVATIVE PLASTICS IP 2016-03-23 CN disclosed
EP-0325719-A2 Melt stable polyetherimide-poly-carbonate blends GENERAL ELECTRIC COMPANY (US) 1989-08-02 EP disclosed
EP-0325718-A2 Ternary polymer blends containing a polyetherimide, a polyphthalate carbonate, and rubber modified vinyl aromatic polymer GENERAL ELECTRIC COMPANY (US) 1989-08-02 EP disclosed
EP-0325130-A2 Substituted pyridines BAYER AG (DE) 1989-07-26 EP disclosed
US-4612400-A Autoxidation of bis(ortho dialkyl-phenoxy)benzophenones THE DOW CHEMICAL COMPANY (US) 1986-09-16 US disclosed
EP-0181000-A2 Foamable polyetherimide resin formulation GENERAL ELECTRIC COMPANY (US) 1986-05-14 EP disclosed
US-4577034-A Autoxidation of bis(ortho dialkyl-phenoxy)benzophenones THE DOW CHEMICAL COMPANY (US) 1986-03-18 US disclosed
EP-0158734-A1 Thermally stabilized polyetherimides GENERAL ELECTRIC COMPANY (US) 1985-10-23 EP disclosed
US-4543368-A DIHYDRODIAZINONE BLOWING AGENT GENERAL ELECTRIC COMPANY (US) 1985-09-24 US disclosed
US-4508861-A CONTAINING ANTIOXIDANT SELECTED FROM HINDERED PHENOLS, ARYL PHOSPHONITES, ORGANIC PHOSPHITES, THIOESTERS OR MIXTURES GENERAL ELECTRIC COMPANY (US) 1985-04-02 US disclosed