Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850760 | 0.80 | SLC1A3 (0.41) | NOS1NOS3NOS2SLC7A5KMT2A | |
| SCHEMBL3428446 | 0.80 | SLC1A3 (0.41) | NOS1NOS3NOS2SLC7A5KMT2A | |
| SCHEMBL27605009 | 0.79 | SLC1A1 (0.50) | SLC7A5KMT2AMEN1PPARGPPARA | |
| SCHEMBL27656864 | 0.77 | KMT2A (0.39) | NOS1NOS3NOS2SLC7A5KMT2A | |
| SCHEMBL4106257 | 0.77 | KMT2A (0.39) | NOS1NOS3NOS2SLC7A5KMT2A | |
| SCHEMBL7814662 | 0.77 | NOS1 (0.37) | NOS1NOS3NOS2SLC7A5KMT2A | |
| SCHEMBL31733944 | 0.77 | NOS1 (0.37) | NOS1NOS3NOS2SLC7A5KMT2A | |
| SCHEMBL1066621 | 0.77 | KMT2A (0.39) | NOS1NOS3NOS2SLC7A5KMT2A | |
| SCHEMBL4936742 | 0.76 | SLC1A2 (0.37) | NOS1NOS3NOS2SLC7A5KMT2A | |
| SCHEMBL4936597 | 0.76 | SLC1A2 (0.37) | NOS1NOS3NOS2SLC7A5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103476767-A | Heterocyclic compounds as PI3 kinase inhibitors | HOFFMANN LA ROCHE | 2013-12-25 | — | — | CN | disclosed |