Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428450 | 0.81 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL27850761 | 0.81 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL3286466 | 0.81 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL1422856 | 0.81 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL27807040 | 0.80 | L3MBTL1 (0.34) | DGAT1 | |
| SCHEMBL27807043 | 0.80 | L3MBTL1 (0.34) | DGAT1 | |
| SCHEMBL6372947 | 0.78 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL28721112 | 0.77 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL4366519 | 0.77 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL609386 | 0.77 | DGAT1 (0.39) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103476767-A | Heterocyclic compounds as PI3 kinase inhibitors | HOFFMANN LA ROCHE | 2013-12-25 | — | — | CN | disclosed |