Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27700199 | 0.83 | CES2 (0.46) | MEN1KMT2ATSHRMMP12ALDH1A1 | |
| SCHEMBL218138 | 0.83 | HTT (0.45) | HTTCYP2C9CYP2C19TSHRMMP12 | |
| SCHEMBL13027401 | 0.83 | HTT (0.45) | HTTCYP2C9CYP2C19TSHRMMP12 | |
| SCHEMBL30967888 | 0.78 | HTT (0.37) | HTTCYP2C9CYP2C19TSHRCYP3A4 | |
| SCHEMBL29237497 | 0.78 | HTT (0.37) | HTTCYP2C9CYP2C19TSHRCYP3A4 | |
| SCHEMBL27821004 | 0.76 | HTT (0.38) | HTTCYP2C9CYP2C19TSHRCYP3A4 | |
| SCHEMBL27854073 | 0.76 | MEN1 (0.49) | MEN1KMT2AMMP12ALDH1A1CYP3A4 | |
| SCHEMBL22201771 | 0.75 | CES2 (0.45) | MEN1KMT2ATSHRMMP12ALDH1A1 | |
| SCHEMBL29237654 | 0.75 | PTGS2 (0.44) | HTTMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL30967948 | 0.75 | PTGS2 (0.44) | HTTMEN1KMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201262-A | Autotaxin inhibitors and uses thereof | AMIRA PHARMACEUTICALS INC | 2013-07-10 | — | — | CN | disclosed |