Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27931886 | 0.82 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL19767298 | 0.79 | L3MBTL1 (0.42) | HDAC6L3MBTL1DGAT1KDM4EPOLB | |
| SCHEMBL28806907 | 0.78 | SCN5A (0.46) | HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL7909762 | 0.77 | RUNX1 (0.40) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL3816388 | 0.75 | NNMT (0.48) | L3MBTL1LMNAHAO1KDM4ECHRNB2 | |
| SCHEMBL29525223 | 0.75 | NNMT (0.48) | L3MBTL1LMNAHAO1KDM4ECHRNB2 | |
| SCHEMBL2714106 | 0.75 | L3MBTL1 (0.43) | L3MBTL1DGAT1TRPV1POLB | |
| SCHEMBL4550334 | 0.75 | L3MBTL1 (0.40) | L3MBTL1DGAT1POLB | |
| SCHEMBL27775336 | 0.74 | KDM4E (0.41) | SMN1; SMN2HAO1KDM4EPOLBRAB9A | |
| SCHEMBL27988925 | 0.74 | L3MBTL1 (0.45) | L3MBTL1TSHRSMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249721-A | Arylamine Derivatives as TTX-S Blockers | RAQUALIA PHARMA INC | 2013-08-14 | — | — | CN | disclosed |