SCHEMBL27932136

SCHEMBL27932136

O=P(OCl)(OCl)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MCHR1 Q99705 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALOX15 P16050 3/20 0.31
ALOX12 P18054 2/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544825 0.87 HSD17B10 (0.39) HSD17B10MEN1KMT2AMCHR1CYP3A4
SCHEMBL28490455 0.83 HSD17B10 (0.37) HSD17B10MEN1KMT2AMCHR1CYP3A4
SCHEMBL29893206 0.78 HSD17B10 (0.37) HSD17B10MEN1KMT2AMCHR1CYP3A4
SCHEMBL15106145 0.78 CYP3A4 (0.47) HSD17B10MEN1KMT2AMCHR1CYP3A4
SCHEMBL1901599 0.74 HSD17B10 (0.41) HSD17B10MEN1KMT2AMCHR1CYP3A4
SCHEMBL28736776 0.74 HSD17B10 (0.41) HSD17B10MEN1KMT2AMCHR1CYP3A4
SCHEMBL9504804 0.74 INPPL1 (0.48) HSD17B10MEN1KMT2AMCHR1CYP3A4
SCHEMBL11586247 0.74 HSD17B10 (0.41) HSD17B10MEN1KMT2AMCHR1CYP3A4
SCHEMBL10449063 0.73 SRC (0.42) HSD17B10MEN1KMT2AMCHR1CYP3A4
SCHEMBL11300689 0.73 SRC (0.42) HSD17B10MEN1KMT2AMCHR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103224518-A Synthesis method of phosphoric acid three (three bromo phenyl) ester Tianjin lianrui flame retardant material co ltd 2013-07-31 CN disclosed