SCHEMBL544825

SCHEMBL544825

O=P(Oc1c(Br)cc(Br)cc1Br)(Oc1c(Br)cc(Br)cc1Br)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 3/20 0.36
CYP3A4 P08684 3/20 0.36
TSHR P16473 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HSP90AA1 P07900 1/20 0.36
TLR9 Q9NR96 1/20 0.36
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 2/20 0.34
ALOX15 P16050 4/20 0.34
ALOX12 P18054 3/20 0.34
MCHR1 Q99705 1/20 0.34
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32
AKR1B1 P15121 1/20 0.31
AKR1C4 P17516 1/20 0.31
AKR1C3 P42330 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28490455 0.91 HSD17B10 (0.37) HSD17B10TDP1CYP3A4TSHRMEN1
SCHEMBL15106145 0.89 CYP3A4 (0.47) HSD17B10TDP1CYP3A4TSHRMEN1
SCHEMBL27932136 0.87 HSD17B10 (0.35) HSD17B10TDP1CYP3A4TSHRMEN1
SCHEMBL10449063 0.84 SRC (0.42) HSD17B10TDP1CYP3A4TSHRMEN1
SCHEMBL11300689 0.84 SRC (0.42) HSD17B10TDP1CYP3A4TSHRMEN1
SCHEMBL11292409 0.83 KDM4E (0.38) HSD17B10TDP1CYP3A4TSHRMEN1
SCHEMBL11301633 0.82 CYP3A4 (0.63) HSD17B10TDP1CYP3A4TSHRMEN1
SCHEMBL1901599 0.81 HSD17B10 (0.41) HSD17B10TDP1CYP3A4TSHRMEN1
SCHEMBL11586247 0.81 HSD17B10 (0.41) HSD17B10TDP1CYP3A4TSHRMEN1
SCHEMBL11572063 0.81 ALDH1A1 (0.52) HSD17B10TDP1CYP3A4TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552500-A Process for the preparation of polyamide materials with improved long-term use L.布吕格曼两合公司 2025-03-04 CN claimed
CN-114806103-A Anti-dripping self-reinforced copolyester and preparation method thereof 波塞冬(江苏)新材料科技有限公司 2022-07-29 CN claimed
EP-3526281-A1 PROCESS FOR PREPARING POLYAMIDE MATERIALS HAVING IMPROVED LONG-TERM USE PROPERTIES L. Brüggemann GmbH & Co. KG (DE) 2019-08-21 EP claimed
US-20190248986-A1 PROCESS FOR THE PREPARATION OF POLYAMIDE MATERIALS WITH IMPROVED LONG-TERM PROPERTIES L. BRÜGGEMANN GMBH & CO. KG (DE) 2019-08-15 US claimed
US-5393812-A A polyolefin, a halogenated hydrocarbyl phosphate or phosphonate ester, and an alkoxyamine functional hindered amine HERCULES INCORPORATED (US) 1995-02-28 US claimed
EP-0401198-A1 Polybrominated phenylphosphate flame retardant thermoplastic composition FMC Corporation (US) 1990-12-05 EP claimed
EP-0333694-A2 Polybrominated phenylphosphate flame retardant thermoplastic composition FMC Corporation (US) 1989-09-20 EP claimed
US-4170614-A HYDROLYSIS OF TRIS(2,6-DIHALOPHENYL) PHOSPHATE PPG INDUSTRIES, INC. (US) 1979-10-09 US claimed
US-4021406-A PHOSPHOROUS COMPOUNDS M & T CHEMICALS INC. (US) 1977-05-03 US claimed
JP-6263977-A None JP disclosed
CN-120040939-A Polycarbonate composition and molded article 帝人株式会社 2025-05-27 CN disclosed
CN-119552500-A Process for the preparation of polyamide materials with improved long-term use L.布吕格曼两合公司 2025-03-04 CN disclosed
EP-4474426-A1 POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED OBJECT Kaneka Corporation (JP) 2024-12-11 EP disclosed
CN-118574893-A Polycarbonate resin composition and molded article 株式会社钟化 2024-08-30 CN disclosed
US-4111905-A ZINC SULFIDE AND MAGNESIUM HYDROXIDE, CALCIUM HYDROXIDE, BARIUM SULFATE, OR HYDRATED ALUMINA M&T CHEMICALS INC. (US) 1978-09-05 US disclosed
US-4059655-A REACTING A 2,6-DIHALOPHENOL WITH PHOSPHORUS OXYHALIDE, HYDROLYSIS PPG INDUSTRIES, INC. (US) 1977-11-22 US disclosed
US-4055702-A POLYESTER, POLYAMIDE, POLYETHYLENE OR POLYPROPYLENE M & T CHEMICALS INC. (US) 1977-10-25 US disclosed
US-4033927-A PHOSPHONATES GENERAL ELECTRIC COMPANY (US) 1977-07-05 US disclosed
US-4021406-A PHOSPHOROUS COMPOUNDS M & T CHEMICALS INC. (US) 1977-05-03 US disclosed
US-4001367-A COLD DRAWING FIBERS TO CREATE MICROVOIDS, FILLING WITH FIREPROOFING AGENT M & T CHEMICALS INC. (US) 1977-01-04 US disclosed