SCHEMBL9504804

SCHEMBL9504804

O=P(O)(O)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 10/20 0.48
INPP5A Q14642 6/20 0.47
AKT1 P31749 1/20 0.46
INPP5B P32019 2/20 0.46
SRC P12931 3/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALOX15 P16050 3/20 0.36
ALOX12 P18054 2/20 0.36
MCHR1 Q99705 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27525487 0.98 INPPL1 (0.47) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL1901599 0.86 HSD17B10 (0.41) INPPL1INPP5AAKT1INPP5BHSD17B10
SCHEMBL28736776 0.86 HSD17B10 (0.41) INPPL1INPP5AAKT1INPP5BHSD17B10
SCHEMBL20184822 0.84 HSD17B10 (0.37) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL9350985 0.83 INPPL1 (0.45) INPPL1INPP5AAKT1INPP5BSRC
Bromofenofos SCHEMBL29388033 0.82 GABRA1 (0.57) INPPL1INPP5AAKT1INPP5BSRC
Bromofenofos SCHEMBL1338224 0.82 GABRA1 (0.57) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL544825 0.81 HSD17B10 (0.39) HSD17B10CYP3A4TSHRTDP1MEN1
SCHEMBL9417194 0.78 INPPL1 (0.41) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL11671756 0.78 INPPL1 (0.38) INPPL1INPP5AAKT1INPP5BSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101275010-A Flame-proof reinforced Valox compound and preparation thereof SHANGHAI KINGFA SCI & TECH CO (CN) 2008-10-01 CN claimed
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed
EP-4087896-A1 POLYAMIDE MATERIALS HAVING IMPROVED LONG-TERM PERFORMANCE CHARACTERISTICS L. Brüggemann GmbH & Co. KG (DE) 2022-11-16 EP disclosed
WO-2021140246-A1 POLYAMIDE MATERIALS HAVING IMPROVED LONG-TERM PERFORMANCE CHARACTERISTICS L. BRÜGGEMANN GMBH & CO. KG (DE) 2021-07-15 WO disclosed
CN-102725275-B Bibenzoxazinone compounds TEIJIN CHEMICALS LTD 2015-06-10 CN disclosed
CN-102712807-B Polycarbonate resin composition TEIJIN CHEMICALS LTD 2014-09-03 CN disclosed
CN-101525481-B Flame-retardant aromatic polycarbonate resin TEIJIN CHEMICALS LTD 2013-11-13 CN disclosed
CN-102015892-B Flame-retardant polycarbonate resin composition TEIJIN CHEMICALS LTD 2013-09-25 CN disclosed
CN-103224518-A Synthesis method of phosphoric acid three (three bromo phenyl) ester Tianjin lianrui flame retardant material co ltd 2013-07-31 CN disclosed
CN-102449066-B Polycarbonate resin composition and molded article comprising same TEIJIN CHEMICALS LTD 2013-07-24 CN disclosed
CN-1216940-C Aromatic polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2005-08-31 CN disclosed
CN-1590458-A Thermoplastic resin composition and shaped article DAICEL POLYMER LTD (JP) 2005-03-09 CN disclosed
CN-1427871-A Aromatic polycarbonate resin composition TEIJIN CHEMICALS LTD (JP) 2003-07-02 CN disclosed
EP-0244393-B1 FLAME RETARDANT POLYPHENYLENE ETHER MOLDING COMPOSITIONS FMC Corporation (US) 1993-06-23 EP disclosed
EP-0401198-A1 Polybrominated phenylphosphate flame retardant thermoplastic composition FMC Corporation (US) 1990-12-05 EP disclosed
EP-0333694-A2 Polybrominated phenylphosphate flame retardant thermoplastic composition FMC Corporation (US) 1989-09-20 EP disclosed
US-4710530-A CONTAINING POLYBROMOTRIPHENYL PHOSPHATES FMC CORPORATION (US) 1987-12-01 US disclosed
EP-0244393-A2 Flame retardant polyphenylene ether molding compositions FMC Corporation (US) 1987-11-04 EP disclosed
US-4170614-A HYDROLYSIS OF TRIS(2,6-DIHALOPHENYL) PHOSPHATE PPG INDUSTRIES, INC. (US) 1979-10-09 US disclosed
US-4059655-A REACTING A 2,6-DIHALOPHENOL WITH PHOSPHORUS OXYHALIDE, HYDROLYSIS PPG INDUSTRIES, INC. (US) 1977-11-22 US disclosed