Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28810181 | 0.96 | CDC25A (0.31) | CDC25ACDC25B | |
| Bromide SCHEMBL27948568 | 0.96 | CDC25A (0.31) | CDC25ACDC25B | |
| Fluoride Ion SCHEMBL27948693 | 0.96 | CDC25A (0.31) | CDC25ACDC25B | |
| Hydrochloric Acid SCHEMBL4089359 | 0.78 | CYP11B1 (0.33) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL28072065 | 0.77 | CDC25A (0.31) | CDC25ACDC25BCYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL6221557 | 0.77 | CDC25A (0.34) | CDC25ACDC25BCYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL27932951 | 0.77 | CDC25A (0.31) | CDC25ACDC25BCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL574074 | 0.76 | HTR2A (0.33) | CDC25ACDC25B | |
| SCHEMBL5160641 | 0.76 | CDC25A (0.32) | CDC25ACDC25B | |
| SCHEMBL4652033 | 0.76 | HTR2A (0.33) | CDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443171-B | Polyethylene film | 伊奎斯塔化学有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-103509060-B | Metallocene compound, the carbon monoxide-olefin polymeric comprising metallocene compound and the olefine polymerizing process of use metallocene compound | 大林产业株式会社 | 2016-08-10 | — | — | CN | disclosed |
| CN-105793326-A | Moisture-curable compositions with metal-arene complexes | 莫门蒂夫性能材料股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-103509060-A | Metallocene compound, catalyst composite containing metallocene compound and olefin polymerization method using metallocene compound | DAELIM IND CO LTD | 2014-01-15 | — | — | CN | disclosed |