Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL27948797 | 0.96 | LMNA (0.31) | LMNATSHRALOX12ACHE | |
| Bromide SCHEMBL27933161 | 0.96 | HTR2A (0.33) | LMNATSHRALOX12ACHE | |
| Iodide SCHEMBL27477264 | 0.96 | LMNA (0.31) | LMNATSHRALOX12ACHE | |
| Hydrochloric Acid SCHEMBL27933249 | 0.78 | CDC25A (0.31) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL4314163 | 0.76 | CYP2A6 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4092756 | 0.76 | MAOA (0.33) | — | |
| Hydrochloric Acid SCHEMBL1539640 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1LMNATSHR | |
| SCHEMBL4094216 | 0.76 | LMNA (0.32) | CYP11B1CYP11B2CYP19A1LMNATSHR | |
| Hydrochloric Acid SCHEMBL27484580 | 0.75 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8149969 | 0.75 | LMNA (0.35) | CYP11B1CYP11B2CYP19A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023532-A | Preparation method of saturated metallocene poly alpha-olefin | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116023562-A | Production process of poly alpha-olefin | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116023534-A | Preparation method of poly alpha-olefin | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116020416-A | Method for removing metallocene catalyst | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-111491959-B | Film made of polyethylene composition and method for producing same | 埃克森美孚化学专利公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-112218900-B | Catalyst system comprising two hafnocene catalyst compounds | 埃克森美孚化学专利公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-111587256-B | Catalyst system and polymerization process using the same | 埃克森美孚化学专利公司 | 2023-05-19 | — | — | CN | disclosed |
| CN-112384541-B | Process for the preparation of heterophasic polyethylene particles | 埃克森美孚化学专利公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116023532-A | Preparation method of saturated metallocene poly alpha-olefin | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116023562-A | Production process of poly alpha-olefin | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116023534-A | Preparation method of poly alpha-olefin | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116020416-A | Method for removing metallocene catalyst | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| WO-2001043862-A1 | METHOD AND DOSING DEVICE FOR THE CONTROLLED INTRODUCTION OF SOLIDS INTO PRESSURIZED ROOMS | BASELL POLYOLEFINE GMBH (DE) | 2001-06-21 | — | — | WO | disclosed |
| WO-2000078823-A1 | SUPPORT CATALYST FOR OLEFIN POLYMERIZATION | BASELL POLYOLEFINE GMBH (DE) | 2000-12-28 | — | — | WO | disclosed |
| EP-1053265-A1 | INJECTION-STRETCH-BLOW MOULDED CONTAINERS MADE OF OLEFIN POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-22 | — | — | EP | disclosed |
| CN-1274359-A | Mu-oxometallocene complex compound, and olefin polymerization catalyst and polymerization method using same | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1274360-A | Processes for prepn. of metallocene complexes | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |
| WO-1999041293-A1 | INJECTION-STRETCH-BLOW MOULDED CONTAINERS MADE OF OLEFIN POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-19 | — | — | WO | disclosed |
| US-5837764-A | BLEND WITH ETHYLENE-PROPYLENE BLOCK COPOLYMER; STIFFNESS, NONDEFORMING, HEAT RESISTANCE, IMPACT STRENGTH, MOLDABILITY; AUTOMOBILE INSTRUMENT PANELS | UBE INDUSTRIES, LTD. (JP) | 1998-11-17 | — | — | US | disclosed |
| CN-1160055-A | Process for reducing by-product in product mixture | HOECHST AG (DE) | 1997-09-24 | — | — | CN | disclosed |