Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327553 | 0.81 | PLA2G1B (0.40) | ALDH1A1KMT2AMEN1POLBS1PR1 | |
| SCHEMBL326617 | 0.78 | MCHR1 (0.47) | KMT2AMEN1POLBS1PR1S1PR5 | |
| SCHEMBL27933607 | 0.74 | S1PR1 (0.38) | ALDH1A1KMT2APOLBS1PR1S1PR5 | |
| SCHEMBL23230109 | 0.66 | ALDH1A1 (0.47) | ALDH1A1POLBGAAKDM4ELMNA | |
| SCHEMBL1269135 | 0.65 | OPRL1 (0.58) | ALDH1A1KMT2AMEN1POLBGAA | |
| SCHEMBL17696097 | 0.64 | HTR3E (0.57) | KMT2AMEN1LMNA | |
| SCHEMBL18212504 | 0.62 | S1PR1 (0.44) | ALDH1A1KMT2AMEN1POLBGAA | |
| SCHEMBL21075502 | 0.62 | POLB (0.49) | ALDH1A1POLBGAAS1PR1S1PR5 | |
| SCHEMBL31202932 | 0.62 | NR1H2 (0.50) | ALDH1A1KMT2AMEN1POLBGAA | |
| SCHEMBL19311866 | 0.60 | KDM4E (0.42) | ALDH1A1KMT2AMEN1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103209979-A | Therapeutic agent 976 | ASTRAZENECA AB | 2013-07-17 | — | — | CN | disclosed |