SCHEMBL27933725

SCHEMBL27933725

COc1cccc(Nc2ccccc2)c1N

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.62
ALDH1A1 P00352 7/20 0.62
MAPK1 P28482 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
GAA P10253 5/20 0.50
KDM4E B2RXH2 4/20 0.50
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
RAB9A P51151 5/20 0.47
TDP1 Q9NUW8 3/20 0.47
RECQL P46063 2/20 0.47
THRB P10828 1/20 0.47
HTT P42858 1/20 0.47
MMP14 P50281 1/20 0.47
GLA P06280 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2095055 0.83 MAPT (0.72) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL29744518 0.83 MAPT (0.72) MAPTALDH1A1MAPK1L3MBTL1GAA
Hydrochloric Acid SCHEMBL7128944 0.81 MAPT (0.70) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL31099173 0.80 RAB9A (0.60) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL18550733 0.80 MAPT (0.54) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL30354998 0.80 RAB9A (0.60) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL7394126 0.79 MAPT (0.53) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL1118833 0.79 MAPT (0.53) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL194451 0.77 ALDH1A1 (0.46) MAPTALDH1A1MAPK1L3MBTL1GAA
SCHEMBL5923796 0.77 MAPT (0.81) MAPTALDH1A1MAPK1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107118346-B The method of one-step synthesis method aniline-aniline derivatives composition copolymer cladding magnetic nanoparticle 邢台学院 2019-05-28 CN disclosed
CN-103257501-B A kind of electrochromism fabric based on polyaniline and preparation method thereof Institute of Military Equipment, General Logistics of People's Liberation Army of China (CN) 2016-03-02 CN disclosed
CN-103257501-A Polyaniline based electrochromic fabric and manufacturing method thereof QM EQUIP RES INST DEPT PLA 2013-08-21 CN disclosed