Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782445 | 0.85 | KDM4E (0.38) | KDM4EPOLBRAB9AADRA2AADRA2B | |
| SCHEMBL30189703 | 0.85 | KDM4E (0.38) | KDM4EPOLBRAB9AADRA2AADRA2B | |
| SCHEMBL27933780 | 0.80 | GBA1 (0.41) | KDM4ERAB9AADRA2AADRA2BADRA2C | |
| SCHEMBL31508083 | 0.72 | CA12 (0.41) | KDM4EPOLBRAB9AADRA2AADRA2B | |
| SCHEMBL747715 | 0.71 | — | — | |
| SCHEMBL30912708 | 0.71 | — | — | |
| SCHEMBL28151818 | 0.71 | — | — | |
| SCHEMBL852810 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL27686002 | 0.70 | ADRA2A (0.44) | KDM4ERAB9AADRA2AADRA2BADRA2C | |
| SCHEMBL15986902 | 0.69 | KDM4E (0.33) | KDM4EPOLBRAB9AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103237800-A | Amide derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP | 2013-08-07 | — | — | CN | disclosed |