Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820902 | 0.85 | GBA1 (0.43) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL12162565 | 0.81 | GBA1 (0.46) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL27933784 | 0.80 | KDM4E (0.36) | KDM4EADRA2AADRA2BADRA2CRAB9A | |
| SCHEMBL14840925 | 0.76 | ALDH1A1 (0.41) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL14102676 | 0.75 | GBA1 (0.41) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL1818218 | 0.75 | GBA1 (0.41) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL23148799 | 0.73 | GBA1 (0.41) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL31207468 | 0.73 | GBA1 (0.41) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL506458 | 0.70 | — | — | |
| SCHEMBL684128 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103237800-A | Amide derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP | 2013-08-07 | — | — | CN | disclosed |