Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | QDPR | P09417 | 4/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27949194 | 0.92 | HDAC1 (0.38) | HDAC1HDAC2HDAC3QDPRNAMPT | |
| SCHEMBL28294631 | 0.86 | HDAC1 (0.40) | HDAC1HDAC2HDAC3QDPRNAMPT | |
| SCHEMBL28123122 | 0.86 | QDPR (0.34) | QDPRNAMPTMGLLPDE4BTPSAB1 | |
| SCHEMBL28123114 | 0.84 | QDPR (0.34) | QDPRNAMPTPDE4BTPSAB1CCR5 | |
| SCHEMBL27945504 | 0.83 | HDAC1 (0.38) | HDAC1HDAC2HDAC3QDPRNAMPT | |
| SCHEMBL27979565 | 0.83 | HDAC1 (0.38) | HDAC1HDAC2HDAC3QDPRNAMPT | |
| SCHEMBL27724744 | 0.83 | HDAC1 (0.38) | HDAC1HDAC2HDAC3QDPRNAMPT | |
| SCHEMBL27933803 | 0.82 | QDPR (0.48) | QDPRPDE4B | |
| SCHEMBL27945028 | 0.81 | CCR5 (0.41) | HDAC1HDAC2HDAC3QDPRPDE4B | |
| SCHEMBL27318172 | 0.79 | SLC18A3 (0.44) | HDAC1HDAC2HDAC3QDPRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106470985-A | Indane and indoline derivatives as soluble guanylate cyclase activators and uses thereof | 诺华股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-103534240-B | Selectivity Fak inhibitor | Cancer Therapeutics CRC Pty Ltd. (AU) | 2015-12-09 | — | — | CN | disclosed |
| CN-103534240-A | Selective FAK inhibitors | CANCER THERAPEUTICS CRC PTY LTD | 2014-01-22 | — | — | CN | disclosed |