Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2264197 | 0.86 | CA2 (0.41) | CA2CA12CA1CA9HPGD | |
| SCHEMBL27694231 | 0.83 | CA2 (0.38) | CA2CA12CA1CA9HPGD | |
| SCHEMBL27696617 | 0.83 | HPGD (0.44) | CA2CA1HPGDUSP2SMN1; SMN2 | |
| Formaldehyde SCHEMBL27870886 | 0.75 | USP2 (0.55) | CA2CA12CA1CA9HPGD | |
| Formaldehyde SCHEMBL27601645 | 0.75 | USP2 (0.55) | CA2CA12CA1CA9HPGD | |
| SCHEMBL22684478 | 0.75 | CA2 (0.37) | CA2CA12CA1CA9HPGD | |
| SCHEMBL1225127 | 0.74 | USP2 (0.58) | CA2CA12CA1CA9HPGD | |
| SCHEMBL1910477 | 0.74 | CA2 (0.34) | CA2CA12CA1CA9HPGD | |
| SCHEMBL12005408 | 0.74 | USP2 (0.58) | CA2CA12CA1CA9HPGD | |
| SCHEMBL8286 | 0.74 | USP2 (0.58) | CA2CA12CA1CA9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103534240-B | Selectivity Fak inhibitor | Cancer Therapeutics CRC Pty Ltd. (AU) | 2015-12-09 | — | — | CN | disclosed |
| CN-103534240-A | Selective FAK inhibitors | CANCER THERAPEUTICS CRC PTY LTD | 2014-01-22 | — | — | CN | disclosed |