Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209174 | 0.98 | HPGD (0.53) | HPGDTP53HSD11B1ALDH1A1ATM | |
| SCHEMBL1595294 | 0.98 | HPGD (0.53) | HPGDTP53HSD11B1ALDH1A1ATM | |
| SCHEMBL4189336 | 0.95 | — | — | |
| SCHEMBL745882 | 0.90 | — | — | |
| SCHEMBL7729860 | 0.88 | HPGD (0.46) | HPGDTP53HSD11B1ALDH1A1ATM | |
| SCHEMBL8788705 | 0.86 | CYP1A2 (0.43) | HPGDTP53ALDH1A1P2RX7NPC1 | |
| SCHEMBL1283873 | 0.84 | CYP1A2 (0.46) | HPGDP2RX7NPC1RAB9AEPHX1 | |
| SCHEMBL6521504 | 0.82 | KDM5A (0.51) | HPGDALDH1A1MEN1KMT2AEPHX1 | |
| SCHEMBL6519311 | 0.82 | KDM5A (0.51) | HPGDALDH1A1MEN1KMT2AEPHX1 | |
| SCHEMBL384147 | 0.82 | KDM5A (0.50) | HPGDMEN1KMT2AEPHX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1020 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552093-A | Preparation method of key intermediate of poncirtinib phosphate | 济南鼎皓医药科技有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-118496175-A | TRADD inhibitor derivative and preparation method and application thereof | 安徽医科大学 | 2024-08-16 | — | — | CN | claimed |
| CN-114957156-A | Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof | 成都科宜高分子科技有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-110643032-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-110643032-A | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2020-01-03 | — | — | CN | claimed |
| CN-106967213-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2019-11-05 | — | — | CN | claimed |
| CN-109629026-A | A kind of cellulose melt spun fibre and preparation method thereof with durable antibiotic performance | 东华大学 | 2019-04-16 | — | — | CN | claimed |
| CN-108329828-A | Resistance to ag(e)ing, water resistance, oil resistivity Water-based ceramic-imitating coating and preparation method thereof | 段宝荣 | 2018-07-27 | — | — | CN | claimed |
| CN-104725628-B | A kind of single functionalization branched polyethylene glycol, preparation method and its bio-related substance containing degradable group | 厦门赛诺邦格生物科技股份有限公司 | 2018-04-17 | — | — | CN | claimed |
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| EP-1506176-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2013-04-24 | — | — | EP | claimed |
| US-7423033-B2 | Hydroxyalkanoylaminolactams and related structures as inhibitors of aβ protein production | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2008-09-09 | — | — | US | claimed |
| US-20080132482-A1 | HYDROXYALKANOYLAMINOLACTAMS AND RELATED STRUCTURES AS INHIBITORS OF A BETA PROTEIN PRODUCTION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2008-06-05 | — | — | US | claimed |
| US-20080064876-A1 | Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione | CELGENE CORPORATION | 2008-03-13 | — | — | US | claimed |
| WO-2007136640-A2 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLE-1,3-DIONE | CELGENE CORPORATION (US) | 2007-11-29 | — | — | WO | claimed |
| US-7271124-B2 | Process to produce polymers | PHILLIPS PETROLEUM COMPANY (US) | 2007-09-18 | — | — | US | claimed |
| US-20060155082-A1 | Process for producing polymers | CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. | 2006-07-13 | — | — | US | claimed |
| US-20040254323-A1 | Process to produce polymers | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2004-12-16 | — | — | US | claimed |
| EP-0440329-A1 | S-substituted carbonyl substituted betathioacrylamide biocides and fungicides | ROHM AND HAAS COMPANY (US) | 1991-08-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132482-A1 | HYDROXYALKANOYLAMINOLACTAMS AND RELATED STRUCTURES AS INHIBITORS OF A BETA PROTEIN PRODUCTION | APP, BACE1, APH1A | HPGD 1597/4885TP53 3452/4885HSD11B1 313/4885 |
| US-20080064876-A1 | Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione | TNF, DHPS, IDO1 | HPGD 175/4885TP53 3271/4885HSD11B1 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.