Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 14/20 | 0.67 |
| ▸ | MAPK12 | P53778 | 14/20 | 0.67 |
| ▸ | MAPK11 | Q15759 | 14/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 14/20 | 0.67 |
| ▸ | RAF1 | P04049 | 10/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.62 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.62 |
| ▸ | GCGR | P47871 | 4/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075623 | 0.88 | MAPK13 (0.71) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL6465030 | 0.85 | MAPK13 (0.71) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL18292684 | 0.84 | MAPT (0.69) | MAPK14MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL67025 | 0.82 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL6469484 | 0.82 | NOX1 (0.88) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7645951 | 0.82 | MAPK13 (0.74) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL69956 | 0.81 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL2949385 | 0.81 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7228717 | 0.81 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL6469341 | 0.81 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102190625-B | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2013-08-28 | — | — | CN | disclosed |