Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acetylcarnitine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylcarnitine SCHEMBL620955 | 1.00 | MEN1 (0.55) | MEN1KMT2ACYP1A2HRH1LMNA | |
| Acetylcarnitine SCHEMBL948558 | 0.99 | MEN1 (0.56) | MEN1KMT2ACYP1A2HRH1LMNA | |
| SCHEMBL15549471 | 0.85 | MEN1 (0.48) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Arginine SCHEMBL27492468 | 0.84 | SLC22A16 (0.49) | MEN1KMT2ACYP2C19MAPTCPT2 | |
| Arginine SCHEMBL27902011 | 0.83 | SLC22A16 (0.50) | MEN1KMT2ACYP2C19MAPTCPT2 | |
| Acetylcarnitine SCHEMBL5429939 | 0.83 | MEN1 (0.65) | MEN1KMT2ACYP1A2HRH1LMNA | |
| Acetylcarnitine SCHEMBL5429930 | 0.83 | MEN1 (0.65) | MEN1KMT2ACYP1A2HRH1LMNA | |
| Acetylcarnitine SCHEMBL6634467 | 0.82 | KMT2A (0.63) | MEN1KMT2ACYP1A2HRH1LMNA | |
| Acetylcarnitine SCHEMBL6634470 | 0.82 | KMT2A (0.63) | MEN1KMT2ACYP1A2HRH1LMNA | |
| Acetylcarnitine SCHEMBL2322752 | 0.82 | MEN1 (0.63) | MEN1KMT2ACYP1A2HRH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110559265-A | preparation method of acetyl L-carnitine arginine dihydrochloride moisture-proof particles | 辽宁科硕营养科技股份有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-110559265-A | preparation method of acetyl L-carnitine arginine dihydrochloride moisture-proof particles | 辽宁科硕营养科技股份有限公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-103491954-A | Use of L-carnitine, salts and derivatives thereof for reducing or preventing fatigue and improving cognitive function | LONZA AG | 2014-01-01 | — | — | CN | disclosed |