Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tetrapropylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28223166 | 0.94 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52LSS | |
| Cetrimonium SCHEMBL28083618 | 0.94 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52LSS | |
| Tetrapropylammonium SCHEMBL27934903 | 0.94 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52SLC22A1 | |
| Acetic Acid SCHEMBL28471365 | 0.89 | DNM1 (0.62) | DNM1APAF1HSP90AA1RAD52LSS | |
| Acetic Acid SCHEMBL23501563 | 0.89 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52LSS | |
| Acetic Acid SCHEMBL5574243 | 0.89 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52LSS | |
| Acetic Acid SCHEMBL3394806 | 0.89 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52LSS | |
| Cetrimonium SCHEMBL241633 | 0.89 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52LSS | |
| Acetic Acid SCHEMBL11125818 | 0.89 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52LSS | |
| Acetic Acid SCHEMBL5574277 | 0.89 | DNM1 (0.68) | DNM1APAF1HSP90AA1RAD52LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103275803-B | Glass grinding fluid and preparation method thereof | UNIV HENAN NORMAL | 2014-06-04 | — | — | CN | claimed |
| CN-103275803-A | Glass grinding fluid and preparation method thereof | UNIV HENAN NORMAL | 2013-09-04 | — | — | CN | claimed |
| CN-103275803-B | Glass grinding fluid and preparation method thereof | UNIV HENAN NORMAL | 2014-06-04 | — | — | CN | disclosed |
| CN-103275803-A | Glass grinding fluid and preparation method thereof | UNIV HENAN NORMAL | 2013-09-04 | — | — | CN | disclosed |