Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.58 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 4/20 | 0.57 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.55 |
| ▸ | GLP1R | P43220 | 4/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809578 | 1.00 | NOD1 (0.58) | NOD1PLA2G2CFAAHPLA2G10GLP1R | |
| SCHEMBL6931475 | 0.90 | NOD1 (0.60) | NOD1PLA2G2CPLA2G10GLP1R | |
| SCHEMBL27949922 | 0.90 | EPHX2 (0.58) | NOD1PLA2G2CFAAHPLA2G10MEN1 | |
| SCHEMBL9441752 | 0.89 | GLP1R (0.61) | NOD1PLA2G2CGLP1R | |
| Hydrogen Sulfide SCHEMBL28113024 | 0.89 | EPHX2 (0.57) | NOD1PLA2G2CFAAHPLA2G10MEN1 | |
| SCHEMBL9517290 | 0.89 | GLP1R (0.61) | NOD1PLA2G2CGLP1R | |
| SCHEMBL6041085 | 0.87 | NOD1 (0.57) | NOD1PLA2G2CFAAHPLA2G10GLP1R | |
| SCHEMBL6041088 | 0.87 | NOD1 (0.57) | NOD1PLA2G2CFAAHPLA2G10GLP1R | |
| SCHEMBL28705590 | 0.85 | NOD1 (0.61) | NOD1PLA2G2CFAAHPLA2G10MEN1 | |
| SCHEMBL28715914 | 0.85 | NOD1 (0.61) | NOD1PLA2G2CFAAHPLA2G10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103561770-A | Succinoyl compounds and their use for treating ischemic injury | ISCHEMIX LLC | 2014-02-05 | — | — | CN | claimed |
| CN-103561770-B | Succinoyl compounds and their use for treating ischemic injury | 艾雪米克斯公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-103561770-A | Succinoyl compounds and their use for treating ischemic injury | ISCHEMIX LLC | 2014-02-05 | — | — | CN | disclosed |