SCHEMBL27935652

SCHEMBL27935652

O=C(NC1CCN(C(=O)O)CC1OCCCF)c1ncc[nH]1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 2/20 0.33
ACKR3 P25106 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27917053 0.90 PTGES (0.34) OPRD1
SCHEMBL27917490 0.89 OPRD1 (0.34) OPRD1ACKR3
SCHEMBL27935653 0.87 JAK3 (0.34) OPRD1
SCHEMBL27916880 0.85 OPRD1 (0.33) OPRD1
SCHEMBL2846963 0.83 MERTK (0.39) ACKR3
SCHEMBL2846959 0.83 MERTK (0.39) ACKR3
SCHEMBL2854036 0.83 JAK3 (0.40)
SCHEMBL2854038 0.83 JAK3 (0.40)
SCHEMBL27935713 0.79 JAK3 (0.36) OPRD1ACKR3
SCHEMBL27917306 0.79 OPRD1 (0.37) OPRD1ACKR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101959882-B Imidazole carbonyl compound DAIICHI SANKYO CO LTD 2013-09-11 CN disclosed