Dl-Tryptophan

Dl-Tryptophan

SCHEMBL27935802

NC(=O)CCC(NC(=O)[C@@H]1CCC(=O)N1)C(=O)O.NC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
MPO P05164 1/20 0.54
MAPT P10636 1/20 0.54
TSHR P16473 1/20 0.54
BLM P54132 1/20 0.54
PMP22 Q01453 1/20 0.54
HIF1A Q16665 1/20 0.54
ITGB2 P05107 1/20 0.49
ICAM1 P05362 1/20 0.49
ITGAL P20701 1/20 0.49
ACE P12821 2/20 0.45
CCKBR P32239 5/20 0.44
ALOX15 P16050 1/20 0.43
KRAS P01116 1/20 0.43
SOS1 Q07889 1/20 0.43
ECE1 P42892 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27831208 0.91 ITGB2 (0.52) MEN1KMT2AITGB2ICAM1ITGAL
SCHEMBL29975855 0.87 CCKBR (0.52) CCKBR
SCHEMBL27765550 0.86 ITGB2 (0.63) MEN1KMT2AITGB2ICAM1ITGAL
SCHEMBL11201374 0.86 ITGB2 (0.63) MEN1KMT2AITGB2ICAM1ITGAL
SCHEMBL11197636 0.86 ITGB2 (0.63) MEN1KMT2AITGB2ICAM1ITGAL
SCHEMBL2790097 0.86 ITGB2 (0.63) MEN1KMT2AITGB2ICAM1ITGAL
SCHEMBL642928 0.86 ITGB2 (0.63) MEN1KMT2AITGB2ICAM1ITGAL
SCHEMBL27765546 0.86 ITGB2 (0.63) MEN1KMT2AITGB2ICAM1ITGAL
Water SCHEMBL11200551 0.86 ITGB2 (0.62) MEN1KMT2AITGB2ICAM1ITGAL
Water SCHEMBL11200545 0.86 ITGB2 (0.62) MEN1KMT2AITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103554221-A Method for preparing active peptides derived from snake venom SHANGHAI INST PHARM INDUSTRY 2014-02-05 CN disclosed