Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.63 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.63 |
| ▸ | ITGAL | P20701 | 4/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | ECE1 | P42892 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642928 | 1.00 | ITGB2 (0.63) | ITGB2ICAM1ITGALALOX15ACE | |
| SCHEMBL27765546 | 1.00 | ITGB2 (0.63) | ITGB2ICAM1ITGALALOX15ACE | |
| SCHEMBL27765550 | 1.00 | ITGB2 (0.63) | ITGB2ICAM1ITGALALOX15ACE | |
| SCHEMBL11197636 | 1.00 | ITGB2 (0.63) | ITGB2ICAM1ITGALALOX15ACE | |
| SCHEMBL11201374 | 1.00 | ITGB2 (0.63) | ITGB2ICAM1ITGALALOX15ACE | |
| Water SCHEMBL11200551 | 0.99 | ITGB2 (0.62) | ITGB2ICAM1ITGALALOX15ACE | |
| Water SCHEMBL11200545 | 0.99 | ITGB2 (0.62) | ITGB2ICAM1ITGALALOX15ACE | |
| SCHEMBL27849701 | 0.91 | ITGB2 (0.54) | ITGB2ICAM1ITGALACEECE1 | |
| SCHEMBL27831208 | 0.89 | ITGB2 (0.52) | ITGB2ICAM1ITGALACEECE1 | |
| SCHEMBL27831315 | 0.89 | GHSR (0.52) | ITGB2ICAM1ITGALACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100163070-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE | L'OREAL S.A. (FR) | 2010-07-01 | — | — | US | claimed |
| US-11399611-B2 | Process for straightening keratin fibres with a heating means and denaturing agents | L'OREAL (FR) | 2022-08-02 | — | — | US | disclosed |
| CN-112168846-A | Lactobacillus plantarum TCI378 strain and application of metabolite thereof in fat reduction | 大江生医股份有限公司 | 2021-01-05 | — | — | CN | disclosed |
| US-10092490-B2 | Method for straightening keratinous fibres using heating means and an amide | L'OREAL (FR) | 2018-10-09 | — | — | US | disclosed |
| US-20140326268-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL (FR) | 2014-11-06 | — | — | US | disclosed |
| US-8765107-B2 | Process for straightening keratin fibres with a heating means and denaturing agents | L'OREAL (FR) | 2014-07-01 | — | — | US | disclosed |
| US-20120192888-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L 'Oréal S.A., (FR) | 2012-08-02 | — | — | US | disclosed |
| US-20100163070-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE | L'OREAL S.A. (FR) | 2010-07-01 | — | — | US | disclosed |
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL S.A. (FR) | 2010-02-04 | — | — | US | disclosed |
| EP-0085283-A1 | Pyroglutamyl-tryptophan derivatives, process for their preparation and their therapeutic applications | Società Italo-Britannica L. Manetti - H. Roberts & C. (IT) | 1983-08-10 | — | — | EP | disclosed |
| EP-0085283-A1 | Pyroglutamyl-tryptophan derivatives, process for their preparation and their therapeutic applications | Società Italo-Britannica L. Manetti - H. Roberts & C. (IT) | 1983-08-10 | — | — | EP | disclosed |
| EP-0085283-A1 | Pyroglutamyl-tryptophan derivatives, process for their preparation and their therapeutic applications | Società Italo-Britannica L. Manetti - H. Roberts & C. (IT) | 1983-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120192888-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | ITGB2 1429/4885ICAM1 2345/4885ITGAL 1705/4885 |
| US-11399611-B2 | Process for straightening keratin fibres with a heating means and denaturing agents | KRT18, KRTCAP2, TUBB4A | ITGB2 1429/4885ICAM1 2345/4885ITGAL 1705/4885 |
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | ITGB2 1429/4885ICAM1 2345/4885ITGAL 1705/4885 |
| US-10092490-B2 | Method for straightening keratinous fibres using heating means and an amide | KRT18, TUBB3, KIF5C | ITGB2 3282/4885ICAM1 4599/4885ITGAL 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.