Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2793622 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTUSP30UCHL1 | |
| SCHEMBL13179251 | 0.91 | USP30 (0.44) | ALDH1A1LMNAMAPTUSP30UCHL1 | |
| SCHEMBL12566975 | 0.91 | PRMT5 (0.43) | ALDH1A1LMNAMAPTGCKNPC1 | |
| SCHEMBL883261 | 0.90 | USP30 (0.43) | ALDH1A1LMNAMAPTUSP30UCHL1 | |
| SCHEMBL883274 | 0.90 | USP30 (0.43) | ALDH1A1LMNAMAPTUSP30UCHL1 | |
| SCHEMBL16199205 | 0.88 | NR1I2 (0.43) | ALDH1A1LMNAMAPTUSP30GCK | |
| SCHEMBL1983248 | 0.88 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTUSP30UCHL1 | |
| SCHEMBL1983247 | 0.88 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTUSP30UCHL1 | |
| SCHEMBL1987265 | 0.88 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTUSP30UCHL1 | |
| SCHEMBL1987266 | 0.88 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTUSP30UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367824-B1 | Anti-viral derivatives of pyrimidine | ABBVIE INC (US) | 2016-03-23 | — | — | EP | disclosed |
| US-9163017-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140213601-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-8541424-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2013-09-24 | — | — | US | disclosed |
| US-20100168138-A1 | Anti-Viral Compounds | ABBOTT LABORATORIES (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168138-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | ALDH1A1 2858/4885LMNA 3118/4885MAPT 2833/4885 |
| US-20140213601-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | ALDH1A1 2858/4885LMNA 3118/4885MAPT 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.