Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798070 | 0.88 | MAPK14 (0.72) | MAPK14PTGS1PTGS2 | |
| SCHEMBL2516082 | 0.86 | MAPK14 (0.67) | MAPK14PTGS1PTGS2 | |
| SCHEMBL2513403 | 0.86 | MAPK14 (0.67) | MAPK14PTGS1PTGS2 | |
| SCHEMBL2516749 | 0.82 | PTGS2 (0.67) | MAPK14PTGS1PTGS2 | |
| SCHEMBL3890113 | 0.82 | MAPT (0.54) | MAPK14ADORA2AADORA2BADORA1 | |
| SCHEMBL6507852 | 0.81 | MAPK14 (0.82) | MAPK14 | |
| SCHEMBL3890022 | 0.81 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL2792366 | 0.80 | PTGDR2 (0.47) | MAPK14PTGS2ADORA2AADORA2BADORA1 | |
| SCHEMBL2517623 | 0.79 | MAPK14 (0.66) | MAPK14PTGS1PTGS2 | |
| SCHEMBL3888116 | 0.79 | MAPK14 (0.77) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198426-B2 | Use of 5 pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER CORPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | PIR, PNPO, PDXK | MAPK14 1979/4885PTGS1 2640/4885PTGS2 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.