Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403362 | 0.88 | PDK2 (0.45) | RXFP1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL30345614 | 0.88 | THRB (0.52) | RXFP1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL813078 | 0.88 | THRB (0.52) | RXFP1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL17816933 | 0.86 | THRB (0.50) | RXFP1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL11627683 | 0.83 | PDK2 (0.46) | RXFP1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL19039047 | 0.81 | PDK2 (0.50) | P2RX1P2RX3P2RX4P2RX7THRB | |
| SCHEMBL30281291 | 0.81 | PDK2 (0.50) | P2RX1P2RX3P2RX4P2RX7THRB | |
| SCHEMBL18386005 | 0.80 | THRB (0.45) | P2RX1P2RX3P2RX4P2RX7THRB | |
| SCHEMBL13387439 | 0.79 | P2RX1 (0.46) | RXFP1P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL1758787 | 0.76 | P2RX1 (0.53) | P2RX1P2RX3P2RX4P2RX7THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509016-B | Bipyridine fluorene derivatives, preparation method and application thereof, and electroluminescent device | TCL GROUP CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-103509016-B | Bipyridine fluorene derivatives, preparation method and application thereof, and electroluminescent device | TCL GROUP CO LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-103509016-A | Bipyridine fluorene derivatives, preparation method and application thereof, and electroluminescent device | TCL GROUP CO LTD | 2014-01-15 | — | — | CN | disclosed |