Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813078 | 0.98 | THRB (0.52) | THRBTDP1P2RX1P2RX3P2RX4 | |
| SCHEMBL30345614 | 0.98 | THRB (0.52) | THRBTDP1P2RX1P2RX3P2RX4 | |
| SCHEMBL30281291 | 0.90 | PDK2 (0.50) | THRBTDP1P2RX1P2RX3P2RX4 | |
| SCHEMBL19039047 | 0.90 | PDK2 (0.50) | THRBTDP1P2RX1P2RX3P2RX4 | |
| SCHEMBL18386005 | 0.89 | THRB (0.45) | THRBTDP1P2RX1P2RX3P2RX4 | |
| SCHEMBL13387439 | 0.88 | P2RX1 (0.46) | THRBTDP1P2RX1P2RX3P2RX4 | |
| Pyridine SCHEMBL27936442 | 0.86 | RXFP1 (0.45) | THRBTDP1P2RX1P2RX3P2RX4 | |
| SCHEMBL1758787 | 0.85 | P2RX1 (0.53) | THRBTDP1P2RX1P2RX3P2RX4 | |
| SCHEMBL11490930 | 0.85 | CFTR (0.46) | THRBTDP1P2RX1P2RX3P2RX4 | |
| SCHEMBL22876054 | 0.85 | PDK2 (0.50) | THRBTDP1P2RX1P2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10593885-B2 | Polycyclic compound and organic electroluminescence device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-03-17 | — | — | US | disclosed |
| EP-3227269-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-10573818-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-02-25 | — | — | US | disclosed |
| US-20170324037-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-11-09 | — | — | US | disclosed |
| US-20170324037-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-11-09 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| WO-2016087017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10593885-B2 | Polycyclic compound and organic electroluminescence device including the same | ARL1, AR, RIF1 | THRB 3783/4885TDP1 4010/4885P2RX1 1307/4885 |
| US-20170324037-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME | AR, ARL1, ESR2 | THRB 2703/4885TDP1 2393/4885P2RX1 1377/4885 |
| US-20170317283-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, LEF1, EFNA1 | THRB 4547/4885TDP1 1495/4885P2RX1 1976/4885 |
| US-10573818-B2 | Materials for organic electroluminescent devices | PIEZO1, LEF1, EFNA1 | THRB 4547/4885TDP1 1495/4885P2RX1 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.