Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303460 | 0.77 | SCN5A (0.35) | ALDH1A1HSD17B10CYP3A4KMT2AMEN1 | |
| SCHEMBL27950382 | 0.75 | POLB (0.48) | POLBALDH1A1HSD17B10LMNAKMT2A | |
| SCHEMBL5704503 | 0.70 | LMNA (0.41) | ALDH1A1LMNACYP1A2KMT2AMEN1 | |
| SCHEMBL5704543 | 0.70 | — | — | |
| SCHEMBL6553295 | 0.69 | TSHR (0.50) | POLBALDH1A1HSD17B10LMNAKMT2A | |
| SCHEMBL11404233 | 0.69 | ALDH1A1 (0.56) | ALDH1A1HSD17B10LMNACYP1A2CYP3A4 | |
| Fluoride SCHEMBL28135103 | 0.68 | TSHR (0.48) | POLBALDH1A1HSD17B10LMNAKMT2A | |
| SCHEMBL8309821 | 0.68 | MEN1 (0.33) | ALDH1A1LMNACYP1A2KMT2AMEN1 | |
| SCHEMBL272159 | 0.68 | ALDH1A1 (0.54) | ALDH1A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL1457096 | 0.67 | KDM4E (0.48) | POLBALDH1A1HSD17B10CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103562237-B | By the polymkeric substance of the carboxylicesters containing silylated amino or thiocarboxylic acid ester functional | BRIDGESTONE CO.,LTD. (JP) | 2016-02-17 | — | — | CN | disclosed |
| CN-103562237-A | Polymers functionalized with a carboxylic or thiocarboxylic ester containing a silylated amino group | BRIDGESTONE CORP | 2014-02-05 | — | — | CN | disclosed |