Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27918158 | 0.98 | KMT2A (0.64) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5470285 | 0.92 | GAA (0.60) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL1491206 | 0.87 | KMT2A (0.64) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4019882 | 0.85 | GAA (0.70) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11120307 | 0.85 | GAA (0.70) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3801245 | 0.85 | GAA (0.65) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL19049601 | 0.85 | KMT2A (0.62) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL13769814 | 0.81 | GAA (0.68) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL18997520 | 0.81 | GAA (0.60) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL27936739 | 0.81 | GAA (0.56) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110337293-A | Therapeutic compound | 新泽西鲁特格斯州立大学 | 2019-10-15 | — | — | CN | claimed |
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | claimed |
| CN-110337293-A | Therapeutic compound | 新泽西鲁特格斯州立大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | disclosed |