Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120307 | 1.00 | GAA (0.70) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL3043141 | 0.90 | GAA (0.60) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL1010647 | 0.90 | GAA (0.60) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL1308333 | 0.89 | ADRA2C (0.60) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL1008507 | 0.88 | GAA (0.58) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL33868 | 0.84 | GAA (0.55) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL531748 | 0.84 | ADRB1 (0.62) | GAAHTTALDH1A1LMNAHPGD | |
| SCHEMBL31321556 | 0.84 | ADRB1 (0.62) | GAAHTTALDH1A1LMNAHPGD | |
| SCHEMBL1035343 | 0.84 | GAA (0.59) | GAAHTTKMT2AMEN1RAB9A | |
| SCHEMBL5678065 | 0.84 | GAA (0.53) | GAAHTTKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10799475-B2 | Substituted phenyl aziridine precursor analogs for inhibiting androgen-independent prostate cancer cell growth | NORTHWESTERN UNIVERSITY (US) | 2020-10-13 | — | — | US | disclosed |
| US-20180344691-A1 | Substituted Phenyl Aziridine Precursor Analogs for Inhibiting Androgen-Independent Prostate Cancer Cell Growth | NORTHWESTERN UNIVERSITY (US) | 2018-12-06 | — | — | US | disclosed |
| US-20170216249-A1 | Substituted Phenyl Aziridine Precursor Analogs for Inhibiting Androgen-Independent Prostate Cancer Cell Growth | NORTHWESTERN UNIVERSITY (US) | 2017-08-03 | — | — | US | disclosed |
| US-20160089354-A1 | Substituted Phenyl Aziridine Precursor Analogs for Inhibiting Androgen-Independent Cancer Cell Growth | NORTHWESTERN UNIVERSITY (US) | 2016-03-31 | — | — | US | disclosed |
| US-20140045938-A1 | Substituted Phenyl Aziridine Precursor Analogs for Inhibiting Androgen-Independent Prostate Cancer Cell Growth | NORTHWESTERN UNIVERSITY (US) | 2014-02-13 | — | — | US | disclosed |
| WO-2009092796-A1 | SYNEPHRINE DERIVATIVES FOR THE TREATMENT OF CANCER | UNIVERSITEIT GENT (BE) | 2009-07-30 | — | — | WO | disclosed |
| US-20090156672-A1 | Substituted Phenyl Aziridine Precursor Analogs as Modulators of Steroid Receptor Activities | NORTHWESTERN UNIVERSITY (US) | 2009-06-18 | — | — | US | disclosed |
| EP-1239850-B1 | USE OF CARBOXY COMPOUNDS SUCH AS 2(4-ACETOXYPHENYL)-2-CHLORO-N-METHYL-ETHYLAMMONIUM CHLORIDE AS ANTI-INFLAMMATORY AGENTS | UNIV GENT (BE) | 2006-10-18 | — | — | EP | disclosed |
| US-7053120-B2 | Use of carboxy compounds such as 2(4-acetoxyphenyl)2-chloro-N-methyl-ethylammonium chloride as anti-inflammatory agents | GENT UNIVERSITEIT (BE) | 2006-05-30 | — | — | US | disclosed |
| US-20030055030-A1 | Use of carboxy compounds such as 2(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride as anti-inflammatory agents | GENT UNIVERSITEIT (BE) | 2003-03-20 | — | — | US | disclosed |
| EP-1239850-A1 | USE OF CARBOXY COMPOUNDS SUCH AS 2(4-ACETOXYPHENYL)-2-CHLORO-N-METHYL-ETHYLAMMONIUM CHLORIDE AS ANTI-INFLAMMATORY AGENTS | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. (BE) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001045693-A1 | USE OF CARBOXY COMPOUNDS SUCH AS 2(4-ACETOXYPHENYL)-2-CHLORO-N-METHYL-ETHYLAMMONIUM CHLORIDE AS ANTI-INFLAMMATORY AGENTS | VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW (BE) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180344691-A1 | Substituted Phenyl Aziridine Precursor Analogs for Inhibiting Androgen-Independent Prostate Cancer Cell Growth | NR5A1, AR, CYP17A1 | GAA 3102/4885HTT 3525/4885KMT2A 1643/4885 |
| US-20160089354-A1 | Substituted Phenyl Aziridine Precursor Analogs for Inhibiting Androgen-Independent Cancer Cell Growth | NR5A1, AR, CYP17A1 | GAA 2882/4885HTT 3840/4885KMT2A 1525/4885 |
| US-20030055030-A1 | Use of carboxy compounds such as 2(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride as anti-inflammatory agents | CCL5, C5AR2, CCL2 | GAA 1738/4885HTT 1644/4885KMT2A 1959/4885 |
| US-20170216249-A1 | Substituted Phenyl Aziridine Precursor Analogs for Inhibiting Androgen-Independent Prostate Cancer Cell Growth | NR5A1, AR, CYP17A1 | GAA 3102/4885HTT 3525/4885KMT2A 1643/4885 |
| US-20140045938-A1 | Substituted Phenyl Aziridine Precursor Analogs for Inhibiting Androgen-Independent Prostate Cancer Cell Growth | NR5A1, AR, CYP17A1 | GAA 3102/4885HTT 3525/4885KMT2A 1643/4885 |
| US-20090156672-A1 | Substituted Phenyl Aziridine Precursor Analogs as Modulators of Steroid Receptor Activities | NR5A1, AR, NR3C1 | GAA 2666/4885HTT 3938/4885KMT2A 1906/4885 |
| US-10799475-B2 | Substituted phenyl aziridine precursor analogs for inhibiting androgen-independent prostate cancer cell growth | NR5A1, AR, CYP17A1 | GAA 3102/4885HTT 3525/4885KMT2A 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.