Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120307 | 0.85 | GAA (0.70) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4019882 | 0.85 | GAA (0.70) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27936738 | 0.81 | KMT2A (0.66) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27918158 | 0.79 | KMT2A (0.64) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2323800 | 0.78 | ADRB1 (0.55) | HTTRAB9AALDH1A1DRD4 | |
| SCHEMBL3043141 | 0.77 | GAA (0.60) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1010647 | 0.77 | GAA (0.60) | GAAHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2325942 | 0.77 | SMN1; SMN2 (0.57) | GAAKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL14022660 | 0.77 | MGLL (0.41) | KMT2AMEN1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL29786223 | 0.77 | ADRB1 (0.56) | HTTKMT2ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110337293-A | Therapeutic compound | 新泽西鲁特格斯州立大学 | 2019-10-15 | — | — | CN | claimed |
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | claimed |
| CN-110337293-A | Therapeutic compound | 新泽西鲁特格斯州立大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | disclosed |