Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27893270 | 0.81 | MAPT (1.00) | MAPTLMNAKDM4EALDH1A1TP53 | |
| SCHEMBL29817530 | 0.81 | MAPT (1.00) | MAPTLMNAKDM4EALDH1A1TP53 | |
| SCHEMBL27921180 | 0.80 | KMT2A (0.56) | MAPTLMNAKDM4EALDH1A1TP53 | |
| SCHEMBL28061972 | 0.80 | HDAC1 (0.71) | MAPTLMNAKDM4EALDH1A1TP53 | |
| SCHEMBL27921178 | 0.79 | MAPT (0.56) | MAPTLMNAKDM4EALDH1A1TP53 | |
| Harman-3-Carboxylic Acid SCHEMBL3967948 | 0.77 | MAPT (0.73) | MAPTLMNAKDM4EALDH1A1TP53 | |
| SCHEMBL2216825 | 0.76 | MAPT (0.77) | MAPTLMNAKDM4EALDH1A1TP53 | |
| SCHEMBL27975334 | 0.76 | MAPT (0.71) | MAPTLMNAKDM4EALDH1A1TP53 | |
| SCHEMBL15427099 | 0.75 | KMT2A (0.77) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL29817732 | 0.71 | MAPT (0.76) | MAPTLMNAKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429198-B | Banisterine derivant and uses thereof | XINJIANG HUASHIDAN MEDICAMENTS RES CO LTD | 2013-10-23 | — | — | CN | disclosed |