Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Harman-3-Carboxylic Acid SCHEMBL3967948 | 0.83 | MAPT (0.73) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL23500386 | 0.83 | MEN1 (0.83) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL27893270 | 0.83 | MAPT (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL29817530 | 0.83 | MAPT (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL27975334 | 0.82 | MAPT (0.71) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL16489363 | 0.82 | MEN1 (1.00) | MEN1KMT2APOLB | |
| SCHEMBL2216825 | 0.81 | MAPT (0.77) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL27939716 | 0.80 | MAPT (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28061969 | 0.79 | MEN1 (0.73) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28168601 | 0.78 | MEN1 (0.83) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859713-A | Banisterine oxazoline derivate and preparation method and application thereof | 华南农业大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105837569-A | Harmaline oxazoline compound and preparation method and application thereof | 华南农业大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-104628723-B | A kind of banisterine benzoyl urea compound and its preparation method and application | SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) | 2016-06-01 | — | — | CN | disclosed |