Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27782508 | 0.93 | EPAS1 (0.38) | EPAS1TLR8KMT2AMEN1TDP1 | |
| SCHEMBL27939733 | 0.83 | LMNA (0.35) | ICAM1SELEKMT2AMEN1TDP1 | |
| SCHEMBL27939741 | 0.82 | EPAS1 (0.38) | EPAS1ICAM1SELETLR8KMT2A | |
| SCHEMBL27804035 | 0.77 | ICAM1 (0.39) | ICAM1SELEHTR2ASLC6A4KCNH2 | |
| SCHEMBL27782507 | 0.75 | SOS1 (0.40) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL27782509 | 0.74 | EPAS1 (0.40) | EPAS1TLR8KMT2AMEN1TDP1 | |
| SCHEMBL3487169 | 0.73 | HTR2A (0.40) | EPAS1ICAM1SELETLR8KMT2A | |
| SCHEMBL3487173 | 0.73 | HTR2A (0.40) | EPAS1ICAM1SELETLR8KMT2A | |
| SCHEMBL14674111 | 0.73 | EPAS1 (0.37) | EPAS1TLR8KMT2AMEN1TDP1 | |
| SCHEMBL14674110 | 0.71 | SLC6A4 (0.39) | EPAS1KMT2AMEN1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679298-B | Fused bicyclic heteroaryl derivatives | DAIICHI SANKYO CO LTD | 2013-10-23 | — | — | CN | disclosed |