Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27782507 | 0.92 | SOS1 (0.40) | LMNAMAPTALDH1A1RAF1HPGD | |
| SCHEMBL27939738 | 0.83 | EPAS1 (0.36) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27804035 | 0.82 | ICAM1 (0.39) | RAF1CHEK2ICAM1SELEEGLN2 | |
| SCHEMBL27804050 | 0.79 | MAPT (0.38) | LMNAMAPTALDH1A1RAF1HPGD | |
| SCHEMBL27782508 | 0.75 | EPAS1 (0.38) | MEN1KMT2ATDP1TBXA2RHTR2A | |
| SCHEMBL27782471 | 0.74 | L3MBTL1 (0.41) | LMNAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL27804090 | 0.74 | SOS1 (0.41) | MAPTCHEK2MAPK14PPARAHIF1A | |
| SCHEMBL31009459 | 0.70 | HTR2A (0.45) | LMNAMAPTALDH1A1RAF1HPGD | |
| SCHEMBL27939741 | 0.69 | EPAS1 (0.38) | LMNAMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL3487172 | 0.69 | HCAR3 (0.40) | LMNAMAPTALDH1A1RAF1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679298-B | Fused bicyclic heteroaryl derivatives | DAIICHI SANKYO CO LTD | 2013-10-23 | — | — | CN | disclosed |