Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1172395 | 0.97 | NOS1 (0.49) | NOS1TDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL1253994 | 0.79 | NOS1 (0.50) | NOS1TDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL9941730 | 0.78 | NOS1 (0.49) | NOS1TDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL837904 | 0.78 | GAA (0.53) | NOS1TDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL1172797 | 0.78 | NOS1 (0.49) | NOS1TDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL1172817 | 0.78 | NOS1 (0.49) | NOS1TDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL1171722 | 0.78 | NOS1 (0.50) | NOS1TDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL2721250 | 0.77 | NOS1 (0.45) | NOS1TDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL2721094 | 0.76 | NOS1 (0.44) | NOS1TDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL29009519 | 0.75 | NOS1 (0.46) | NOS1TDP1TSHRSMN1; SMN2GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347882-A | Substituted N- (1H-indazol-4-yl) imidazo [1,2-a ] pyridine-3-carboxamide compounds as type III receptor tyrosine kinase inhibitors | ARRAY BIOPHARMA INC | 2013-10-09 | — | — | CN | disclosed |