Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636452 | 0.81 | DPP8 (0.47) | KMT2AMAPTSMN1; SMN2TDP1ATM | |
| SCHEMBL520065 | 0.81 | NPC1 (0.59) | KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL783319 | 0.80 | CYP1A2 (0.52) | KMT2AMAPT | |
| SCHEMBL9519331 | 0.80 | ALDH1A1 (0.56) | KMT2AMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL520364 | 0.80 | NPC1 (0.58) | KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8587397 | 0.80 | ALDH1A1 (0.56) | KMT2AMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3039444 | 0.79 | SMN1; SMN2 (0.52) | KMT2AMAPTSMN1; SMN2TDP1ATM | |
| SCHEMBL31350203 | 0.79 | NPC1 (0.57) | KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8327710 | 0.79 | P2RX4 (0.45) | KMT2AMAPTSMN1; SMN2HPGDRAB9A | |
| SCHEMBL4470296 | 0.78 | ALDH1A1 (0.48) | KMT2AMAPTSMN1; SMN2TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103298813-A | Amorphous powder and polymorph of carbapenem derivative, preparation method therefor and use thereof | ZHUHAI EBANG PHARMACEUTICAL CO LTD | 2013-09-11 | — | — | CN | disclosed |